I have no doubt UC4 will play great and look pretty darned good. However, I don't assume it'll win GOTY though just because it's ND. There are several other games coming out that look more compelling to me. Dying Light was one of them. Incredible gameplay that dwarfs any of the gameplay elements of the past UC games IMO.
There will be other contenders and Dying Light is amazing but i just wouldn't bet against Naughty Dog and Uncharted 4. Their track record speaks for itself. They make great games and show up and win all the awards at the end of the year. I don't see this year being any different. Some minds will be blown with UC4.